We demonstrate a laser using material defects known for deleterious microwave absorption in quantum computing. These defects are two-level atomic tunneling systems (TSs), which are manipulated using a uniform swept dc electric field and two ac pump fields. The swept field changes the TS energies. TSs first pass through degeneracy with pump photons, which invert (excite) them with a high probability using rapid adiabatic passage. Population inversion is accomplished in spite of a broad distribution of TS parameters. Afterwards the TSs are brought to degeneracy with the resonator where they emit photons. The emission is found to be dependent on individual cavity-TS interactions, and the narrowing linewidth at increasing photon occupancy indicates stimulated emission. Characterization with a microwave probe shows a transition from ordinary defect loss to negligible microwave absorption, and ultimately to coherent amplification. Thus, instead of absorbing microwave energy, the TSs can be tuned to reduce loss and even amplify signals.